郭勇志(Yung-Chih Kuo)
背景
國立中正大學 化學工程學系 系主任 2018年2月迄今

國立中正大學 化學工程學系 教授 2007年8月迄今
國立臺灣大學 化工博士
電話：05-272-9147, 05-272-0411 ext. 33459
傳真：05-272-1206
電子信箱： chmyck@ccu.edu.tw

學術領域
生醫材料、藥物釋放系統、奈米醫學、癌症治療、中樞神經疾病治療(阿茲海默症、帕
金森氏症、脊椎損傷、腦中風)、組織工程(胰島、神經、軟骨)、血腦屏障、生物物理
、膠體與界面現象。

學術社團
皇家化學會(英國) 會士
亞太化學、生物暨環境工程學會 永久會員
臺灣化學工程師學會 永久會員
臺灣生物技術與生化工程學會 永久會員
中華民國生物醫學工程學會 永久會員
中華民國生醫材料及藥物制放學會 永久會員
中國工程師學會 永久會員
世界華人生物醫學工程協會 會員
歐洲癌症研究學會 會員
歐洲動脈硬化症學會 會員
心血管磁共振學會 會員
美國奈米學會 會員
紐約科學學會 會員
美國科學促進會 會員

榮譽與獎項
石延平教授論文獎 臺灣化學工程師學會 2018年11月
石延平教授論文獎 臺灣化學工程師學會 2017年11月
最佳論文獎 2nd International Conference on Chemical and Polymer Engineering (布
達佩斯) 2016年8月
賴再得教授獎 臺灣化學工程師學會 2015年
大專校院獎勵特殊優秀人才 科技部(國科會、科技部、教育部)
傑出研究獎 國立中正大學 2013年
傑出研究獎 國立中正大學工學院 2010年
最佳論文獎 1st International Conference on Biomedical Electronics and Biomedical
Informatics (羅德島) 2008年8月
青年學者獎 國立中正大學 2003年
文學創作獎 國泰航空 1999年
榮譽會員 斐陶斐榮譽學會 1996年
文學創作獎 國立臺灣大學 1995年
研究論文獎 立青文教基金會 1994年

JOURNAL EDITOR & PANEL COMMITTEE
& MEMBER ORAL DEFENSE COMMITTEE
Journal Editor:

Deputy Editor  Journal of the Taiwan Institute of Chemical Engineers
Panel Committee: 
Panelist for academic research proposal, Chemical Engineering (including Food
Science) in Engineering Department of MOST
Panelist for appeal cases of academic research proposal, Chemical Engineering in
Engineering Department of MOST
Panelist for outstanding young researcher proposal, Chemical Engineering (including
Food Science) in Engineering Department of MOST
Panelist for undergraduate research award, Chemical Engineering (including Food
Science) in Engineering Department of MOST
Panelist for academic and industrial cooperation proposal, Chemical Engineering
(including Food Science) in Engineering Department of NSC
Committee member of reviewer, Precursor and development category, Outcome and
performance of academic and industrial cooperation project, Engineering Department
of MOST

Member Oral Defense Committee:
International reviewer, PhD thesis evaluation, Department of Chemical Engineering,
National Institute of Technology Warangal Andhra Pradesh, India
International reviewer, PhD thesis evaluation, Department of Chemistry,
Pachaiyappa’s College for Men, India
International reviewer, PhD thesis evaluation, Institute of Science, Nirma University,
India

INCUBATION OF TALENTED STUDENTS
1. 2018, 08, 16-18, Financial support of airfare and registration fee from
MOST (I-Yin Chen), The 4th International Conference on Chemical and
Polymer Engineering, Madrid, Spain. 
2. 2017, 06, 23-24, Honorable Mention (Cheng-Chih Hsu), 2017 BEST
Conference & International Symposium on Biotechnology and
Bioengineering, Yunlin, Taiwan, ROC. 

3. 2016, 11, 25-26, Excellent Paper Award (In-Wei Chao), The 63rd Annual
Conference of the Taiwan Institute of Chemical Engineers, Tao-Yuan,
Taiwan, ROC. 
4. 2016, 08, 29-09, 01, Financial support of airfare and registration fee from
MOST (Chia-Hao Lee), The 13th European Biological Inorganic
Chemistry Conference, Budapest, Hungary. 
5. 2016, 08, 22-23, Financial support of airfare and registration fee from
MOST (In-Wei Chao), The 2nd International Conference on Chemical
and Polymer Engineering, Budapest, Hungary. 
6. 2016, 01, 18-19, Financial support of airfare and registration fee from
MOST (I-Hsuan Lee), The 18th International Conference on Nano and
Biomaterials, San Diego, CA, USA.  
7. 2015, 08, 18-20, Financial support of airfare and registration fee from
MOST (Chia-Hao Lee), The 8th Eurobiotechnology Congress, Frankfurt,
Germany. 
8. 2015, 08, 11-13, Financial support of airfare and registration fee from
MOST (Chia-Hao Lee), International Conference and Expo on Drug
Discovery & Designing, Frankfurt, Germany. 
9. 2014, 11, 13-14, Financial support of airfare and registration fee from
MOST (Yu-Chuan Liu), Cell Symposia: Translational Neuroscience:
Bridge the Gap between Basic Research Discoveries and Clinical
Applications, Arlington, Arlington, VA, USA. 
10. 2014, 08, 20-21, Financial support of airfare and registration fee from
MOST (Chun-Yuan Shih-Huang), Process Development for Novel
Biotherapeutic Formats, Boston, MA, USA. 
11. 2014, 08, 11-14, Financial support of airfare and registration fee from
MOST (Tsu-Yu Hong), The Immunotherapies and Vaccines Summit,
Boston, MA, USA. 
12. 2014, 06, 10-13, Financial support of airfare and registration fee from
MOST (Cheng-Chin Wang), 2014 Tissue Engineering and Regenerative
Medicine International Society – EU Chapter Meeting, Genova, Italy. 

13. 2014, 03, 09-10, Financial support of airfare and registration fee from
MOST (Li-Jung Wang), The MacroJournals Conference on Medicine,
Science, and Technology, Monte Carlo, Monaco. 
14. 2013, 08, Financial support of airfare and registration fee from NSC
(Chun-Yuan Shih-Huang), The 2nd International Conference on Tissue
Science & Regenerative Medicine Theme: Transforming Repairs into
Regeneration, Raleigh, NC, USA.  
15. 2013, Financial support of airfare and registration fee from NSC (Cheng-
Chin Wang), Symposium on Nanoparticle-based Technologies for Cell
Tracking, Liverpool, UK.  
16. 2013, Financial support of airfare and registration fee from NSC (Chun-
Wei Chen), Select Biosciences Clinical Translation of Stem Cells
Conference, Palm Springs, CA, USA. 
17. 2013, Financial support of airfare and registration fee from NSC (Ching-
Chun Lin), The 6th International Symposium on the Separation and
Characterization of Natural and Synthetic Macromolecules, Dresden,
Germany. 
18. 2013, Financial support of airfare and registration fee from NSC (Yu-
Hsuan Chang), The 6th International Symposium on the Separation and
Characterization of Natural and Synthetic Macromolecules, Dresden,
Germany. 
19. 2012, Excellent Poster Award (Yu-Hsuan Chang), 2012 Annual Meeting
of Taiwan Colloid and Interface Society, Tainan, Taiwan, ROC. 
20. 2012, Financial support of airfare and registration fee from NSC (Cheng-
Chin Wang), International Congress on Natural Products Research, New
York, NY, USA.  
21. 2012, Financial support of airfare and registration fee from NSC (Chiu-
Yen Chung), International Congress on Natural Products Research, New
York, NY, USA.  

22. 2012, Financial support of airfare and registration fee from NSC (Cheng-
Ting Wang), The 1st International Symposium on Nanomedicine in Drug
Delivery and Cancer Diagnosis, Newark, DE, USA.  
23. 2011, Scholarship (Chin-Lung Lee), Foundation for Promotion of Social
Harmony (LCY Chemical Corp.), Government Information Office (Local
News Department), Taichung, Taiwan, ROC. 
24. 2011, Financial support of airfare and registration fee from NSC (Chin-
Lung Lee), The 17th Young Asian Biochemical Engineers’ Community
Symposium, Incheon, Korea. 
25. 2011, Financial support of airfare and registration fee from NSC (Cheng-
Chin Wang), The 17th Young Asian Biochemical Engineers’ Community
Symposium, Incheon, Korea. 
26. 2011, Financial support of airfare and registration fee from NSC (Chiu-
Yen Chung), The 17th Young Asian Biochemical Engineers’ Community
Symposium, Incheon, Korea. 
27. 2007, Excellent Paper Award (Hung-Hao Chen), The 12th Conference on
Biochemical Engineering, Tao-Yuan, Taiwan, ROC.

著作目錄
SCI期刊論文 (*通訊作者)
1. Kuo, Y. C.*, R. Rajesh, and J. P. Hsu, 2019, "Electrophoretic mobility of
neuron-like cells regenerated from iPSCs with induction of retinoic acid-
and nerve growth factor-loaded solid lipid nanoparticles," J. Taiwan Inst.
Chem. Eng. (accepted).
2. Kuo, Y. C.*, L. J. Wang, and R. Rajesh, 2019, 09, "Targeting human brain
cancer stem cells by curcumin-loaded nanoparticles grafted with anti-
aldehyde dehydrogenase and sialic acid: colocalization of ALDH and
CD44," Mater. Sci. Eng. C 102, 362–372. 
3. Kuo, Y. C.*, and R. Rajesh, 2019, 07, "Challenges in the treatment of
Alzheimer's disease: recent progress and treatment strategies of

pharmaceuticals targeting notable pathological factors," Expert Rev.
Neurother. 19, 623–652. 
4. Kuo, Y. C.* C. H. Lee, and R. Rajesh, 2019, 03, "Iron oxide-entrapped
solid lipid nanoparticles and poly(lactide-co-glycolide) nanoparticles with
surfactant stabilization for antistatic application," J. Mater. Res. Technol.
8, 887–895. 
5. Yang, J. T., Y. C. Kuo*, I. Y. Chen, R. Rajesh, Y. I. Lou, and J. P. Hsu,
2019, 03, "Protection against neurodegeneration in the hippocampus
using sialic acid- and 5-HT-moduline-conjugated lipopolymer
nanoparticles," ACS Biomater. Sci. Eng. 5, 1311–1320. 
6. Kuo, Y. C.*, Y. H. Chang, and R. Rajesh, 2019, 03, "Targeted delivery of
etoposide, carmustine and doxorubicin to human glioblastoma cells using
methoxy poly(ethylene glycol)-poly(ε-caprolactone) nanoparticles
conjugated with wheat germ agglutinin and folic acid," Mater. Sci. Eng. C
96, 114–128.
7. Kuo, Y. C.*, C. L. Chen, and R. Rajesh, 2019, 03, "Optimized liposomes
with transactivator of transcription peptide and anti-apoptotic drugs to
target hippocampal neurons and prevent tau-hyperphosphorylated
neurodegeneration," Acta Biomaterialia 87, 207–222.
8. Kuo, Y. C.* and H. C. Tsai, 2018, 10, "Rosmarinic acid- and curcumin-
loaded polyacrylamide-cardiolipin-poly(lactide-co-glycolide) nanoparticles
with conjugated 83-14 monoclonal antibody to protect β-amyloid-insulted
neurons," Mater. Sci. Eng. C 91, 445–457.  
9. Kuo, Y. C.* and R. Rajesh, 2018, 06, "Current development of nanocarrier
delivery systems for Parkinson’s disease pharmacotherapy," J. Taiwan
Inst. Chem. Eng. 87, 15–25. 
10. Kuo, Y. C.*, I. Y. Chen, and R. Rajesh, 2018, 06, "Use of functionalized
liposomes loaded with antioxidants to permeate the blood–brain barrier
and inhibit β-amyloid-induced neurodegeneration in the brain," J. Taiwan
Inst. Chem. Eng. 87, 1–14. 

11. Kuo, Y. C.*, C. L. Lee, and R. Rajesh, 2018, 05, "Regulation of human
brain vascular pericytes and human astrocytes in a blood–brain barrier
model using human brain microvascular endothelial cells: expression of
TGF-β1, VEGF, MMP-9 and P-gp," J. Taiwan Inst. Chem. Eng. 86,
9–17. 
12. Kuo, Y. C.*, H. F. Ku, and R. Rajesh, 2017, 09, "Chitosan/γ-poly(glutamic
acid) scaffolds with surface-modified albumin, elastin and poly-L-lysine
for cartilage tissue engineering," Mater. Sci. Eng. C 78, 265–277. 
13. Kuo, Y. C.* and R. Rajesh, 2017, 08, "Nerve growth factor-loaded
heparinized cationic solid lipid nanoparticles for regulating membrane
charge of induced pluripotent stem cells during differentiation," Mater.
Sci. Eng. C 77, 680–689. 
14. Kuo, Y. C.* and R. Rajesh, 2017, 08, "A critical overview of therapeutic
strategy and advancement for Alzheimer’s disease treatment," J. Taiwan
Inst. Chem. Eng. 77, 92–105. 
15. Kuo, Y. C.* and I. H. Wang, 2017, 08, "Using catanionic solid lipid
nanoparticles with wheat germ agglutinin and lactoferrin for targeted
delivery of etoposide to glioblastoma multiforme," J. Taiwan Inst. Chem.
Eng. 77, 73–82. 
16. Kuo, Y. C.* and R. Rajesh, 2017, 08, "Guided differentiation and tissue
regeneration of induced pluripotent stem cells using biomaterials," J.
Taiwan Inst. Chem. Eng. 77, 41–53. 
17. Kuo, Y. C.*, C. H. Lee, and R. Rajesh, 2017, 08, "Recent advances in the
treatment of glioblastoma multiforme by inhibiting angiogenesis and
using nanocarrier systems," J. Taiwan Inst. Chem. Eng. 77, 30–40. 
18. Kuo, Y. C.* and C. C. Hsu, 2017, 08, "Anti-melanotransferrin and
apolipoprotein E on doxorubicin-loaded cationic solid lipid nanoparticles
for pharmacotherapy of glioblastoma multiforme," J. Taiwan Inst. Chem.
Eng. 77, 10–20. 
19. Kuo, Y. C.*, Y. C. Liu, and R. Rajesh, 2017, 08, "Pancreatic
differentiation of induced pluripotent stem cells in activin A-grafted

gelatin-poly(lactide-co-glycolide) nanoparticle scaffolds with induction of
LY294002 and retinoic acid," Mater. Sci. Eng. C 77, 386–393. 
20. Kuo, Y. C.* and R. Rajesh, 2017, 08, "Targeted delivery of rosmarinic
acid across the blood–brain barrier for neuronal rescue using
polyacrylamide-chitosan-poly(lactide-co-glycolide) nanoparticles with
surface cross-reacting material 197 and apolipoprotein E," Int. J. Pharm.
528, 228–241. 
21. Kuo, Y. C.* and C. H. Hsueh, 2017, 07, "Neuronal production from
induced pluripotent stem cells in self-assembled collagen-hyaluronic
acid-alginate microgel scaffolds with grafted GRGDSP/Ln5-P4," Mater.
Sci. Eng. C 76, 760–774. 
22. Kuo, Y. C.* and C. W. Tsao, 2017, 04, "Neuroprotection against
apoptosis of SK-N-MC cells using RMP-7- and lactoferrin-grafted
liposomes carrying quercetin," Int. J. Nanomed. 12, 2857–2869. 
23. Kuo, Y. C.*, C. Y. Lin, J. S. Li, and Y. I. Lou, 2017, 03, "Wheat germ
agglutinin-conjugated liposomes incorporated with cardiolipin to improve
neuronal survival in Alzheimer’s disease treatment," Int. J. Nanomed. 12,
1757–1774.  
24. Kuo, Y. C.* and C. W. Chen, 2017, 03, "Neuroregeneration of iPS cells in
polyacrylamide-chitosan inverted colloidal crystal scaffolds with
poly(lactide-co-glycolide) nanoparticles and TATVHL peptide," Tissue
Eng. A 23, 1–12. 
25. Kuo, Y. C.* and Y. J. Lee, 2016, 12, "Rescuing cholinergic neurons from
apoptotic degeneration by targeting of serotonin modulator- and
apolipoprotein E-conjugated liposomes to the hippocampus," Int. J.
Nanomed. 11, 6809–6824. 
26. Kuo, Y. C.* and Y. C. Chen, 2016, 10, "Regeneration of neurite-like cells
from induced pluripotent stem cells in self-assembled hyaluronic acid-
gelatin microhydrogel," J. Taiwan Inst. Chem. Eng. 67, 74–87. 
27. Kuo, Y. C.* and I. H. Wang, 2016, 08, "Enhanced delivery of etoposide
across the blood–brain barrier to restrain brain tumor growth using

melanotransferrin antibody- and tamoxifen-conjugated solid lipid
nanoparticles," J. Drug Target. 24, 645–654. 
28. Kuo, Y. C.* and I. W. Chao, 2016, 04, "Conjugation of melanotransferrin
antibody on solid lipid nanoparticles for mediating brain cancer
malignancy," Biotechnol. Prog. 32, 480–490. 
29. Kuo, Y. C.* and I. H. Lee, 2016, 04, "Delivery of doxorubicin to
glioblastoma multiforme in vitro using solid lipid nanoparticles with
surface aprotinin and melanotransferrin antibody for enhanced
chemotherapy," J. Taiwan Inst. Chem. Eng. 61, 32–45. 
30. Kuo, Y. C.* and C. H. Lee, 2016, 02, "Dual targeting of solid lipid
nanoparticles grafted with 83-14 MAb and anti-EGF receptor for
malignant brain tumor therapy," Life Sci. 146, 222–231. 
31. Kuo, Y. C.* and S. J. Cheng, 2016, 02, "Brain targeted delivery of
carmustine using solid lipid nanoparticles modified with tamoxifen and
lactoferrin for antitumor proliferation," Int. J. Pharm. 499, 10–19.  
32. Kuo, Y. C.* and C. C. Lin, 2015, 04, "Rescuing apoptotic neurons in
Alzheimer’s disease using wheat germ agglutinin-conjugated and
cardiolipin-conjugated liposomes with encapsulated nerve growth factor
and curcumin," Int. J. Nanomed. 10, 2653–2672. 
33. Kuo, Y. C.* and C. H. Lee, 2015, 04, "Inhibition against growth of
glioblastoma multiforme in vitro using etoposide-loaded solid lipid
nanoparticles with p-aminophenyl-α-D-manno-pyranoside and folic acid,"
J. Pharm. Sci. 104, 1804–1814. 
34. Kuo, Y. C.* and C. Y. Lin, 2015, 02, "Targeting delivery of liposomes with
conjugated p-aminophenyl-α-D-manno-pyranoside and apolipoprotein E
for inhibiting neuronal degeneration insulted with β-amyloid peptide," J.
Drug Target. 23, 147–158. 
35. Kuo, Y. C.* and Y. C. Chen, 2015, 02, "Targeting delivery of etoposide to
inhibit the growth of human glioblastoma multiforme using lactoferrin-
and folic acid-grafted poly(lactide-co-glycolide) nanoparticles," Int. J.
Pharm. 479, 138–149. 

36. Kuo, Y. C.* and C. C. Wang, 2015, 01, "Carmustine-loaded catanionic
solid lipid nanoparticles with serotonergic 1B receptor subtype antagonist
for in vitro targeted delivery to inhibit brain cancer growth," J. Taiwan
Inst. Chem. Eng. 46, 1–14. 
37. Kuo, Y. C.* and Y. C. Liu, 2014, 10, "Cardiolipin-incorporated liposomes
with surface CRM197 for enhancing neuronal survival against
neurotoxicity," Int. J. Pharm. 473, 334–344.  
38. Chen, G. J., Y. Z. Su, C. Hsu, Y. L. Lo, S. J. Huang, J. H. Ke, Y. C. Kuo,
and L. F. Wang*, 2014, 09, "Angiopep-pluronic F127-conjugated
superparamagnetic iron oxide nanoparticles as nanotheranostic agents
for BBB targeting," J. Mater. Chem. B 2, 5666–5675. 
39. Wang C. C. and Y. C. Kuo*, 2014, 09, "Capillary electrophoresis of
induced pluripotent stem cells during differentiation toward neurons," J.
Taiwan Inst. Chem. Eng. 45, 2096–2105. 
40. Kuo, Y. C.* and P. R. Chou, 2014, 08, "Neuroprotection against
degeneration of SK-N-MC cells using neuron growth factor-encapsulated
liposomes with surface cereport and transferrin," J. Pharm. Sci. 103,
2484–2497. 
41. Kuo, Y. C.* and C. Y. Shih-Huang, 2014, 07, "Solid lipid nanoparticles
with surface antibody for targeting the brain and inhibiting lymphatic
phagocytosis," J. Taiwan Inst. Chem. Eng. 45, 1154–1163. 
42. Kuo, Y. C.* and C. T. Wang, 2014, 07, "Protection of SK-N-MC cells
against β-amyloid peptide-induced degeneration using neuron growth
factor-loaded liposomes with surface lactoferrin," Biomaterials 35,
5954–5964. 
43. Kuo, Y. C.* and L. J. Wang, 2014, 05, "Transferrin-grafted catanionic
solid lipid nanoparticles for targeting delivery of saquinavir to the brain,"
J. Taiwan Inst. Chem. Eng. 45, 755–763. 
44. Kuo, Y. C.* and T. Y. Hong, 2014, 04, "Delivering etoposide to the brain
using catanionic solid lipid nanoparticles with surface 5-HT-moduline,"
Int. J. Pharm. 465, 132–142. 

45. Kuo, Y. C.* and C. C. Wang, 2014, 01, "Cationic solid lipid nanoparticles
with cholesterol-mediated surface layer for transporting saquinavir to the
brain," Biotechnol. Prog. 30, 198–206. 
46. Chung, C. Y., J. T. Yang, and Y. C. Kuo*, 2013, 12,
"Polybutylcyanoacrylate nanoparticles for delivering hormone response
element-conjugated neurotrophin-3 to the brain of intracerebral
hemorrhagic rats," Biomaterials 34, 9717–9727. 
47. Kuo, Y. C.* and C. Y. Shih-Huang, 2013, 09, "Solid lipid nanoparticles
carrying chemotherapeutic drug across the blood–brain barrier through
insulin receptor-mediated pathway," J. Drug Target. 21, 730–738. 
48. Chung, C. Y., J. T. Yang, and Y. C. Kuo*, 2013, 07,
"Polybutylcyanoacrylate nanoparticle-mediated neurotrophin-3 gene
delivery for differentiating iPS cells into neurons," Biomaterials 34,
5562–5570. 
49. Kuo, Y. C.* and H. F. Ko, 2013, 07, "Targeting delivery of saquinavir to
the brain using 83-14 monoclonal antibody-grafted solid lipid
nanoparticles," Biomaterials 34, 4818–4830. 
50. Kuo, Y. C.* and C. C. Wang, 2013, 04, "Guided differentiation of induced
pluripotent stem cells into neuronal lineage in alginate-chitosan-gelatin
hydrogels with surface neuron growth factor," Colloids Surf. B 104,
194–199. 
51. Kuo, Y. C.* and C. C. Lin, 2013, 03, "Accelerated nerve regeneration
using induced pluripotent stem cells in chitin-chitosan-gelatin scaffolds
with inverted colloidal crystal geometry," Colloids Surf. B 103, 595–600. 
52. Lyu, S. R., Y. C. Kuo*, H. F. Ku, and W. H. Hsieh, 2013, 03,
"Cryopreserved chondrocytes in porous biomaterials with surface elastin
and poly-L-lysine for cartilage regeneration," Colloids Surf. B 103,
304–309. 
53. Kuo, Y. C.* and C. W. Chen, 2013, 02, "Inverted colloidal crystal
scaffolds with induced pluripotent stem cells for nerve tissue
engineering," Colloids Surf. B 102, 789–794. 

54. Kuo, Y. C.* and Y. H. Chang, 2013, 02, "Differentiation of induced
pluripotent stem cells toward neurons in hydrogel biomaterials," Colloids
Surf. B 102, 405–411. 
55. Kuo, Y. C.* and C. C. Wang, 2013, 01, "Cationic solid lipid nanoparticles
with primary and quaternary amines for release of saquinavir and
biocompatibility with endothelia," Colloids Surf. B 101, 101–105. 
56. Kuo, Y. C.* and C. Y. Chung, 2012, 12, "TATVHL peptide-grafted
alginate/poly(γ-glutamic acid) scaffolds with inverted colloidal crystal
topology for neuronal differentiation of iPS cells," Biomaterials 33,
8955–8966. 
57. Kuo, Y. C.* and C. T. Wang, 2012, 12, "Neuronal differentiation of
induced pluripotent stem cells in hybrid polyester scaffolds with
heparinized surface," Colloids Surf. B 100, 9–15. 
58. Kuo, Y. C.* and C. C. Wang, 2012, 08, "Surface molecular composition
and electrical property of cationic solid lipid nanoparticles with assembled
lipid layer mediated by noncovalent interactions," J. Phys. Chem. C 116,
16999–17007. 
59. Kuo, Y. C.* and M. J. Huang, 2012, 08, "Material-driven differentiation of
induced pluripotent stem cells in neuron growth factor-grafted poly(ε-
caprolactone)-poly(β-hydroxybutyrate) scaffolds," Biomaterials 33,
5672–5682. 
60. Kuo, Y. C.* and C. C. Wang, 2012, 05, "Cartilage regeneration by
culturing chondrocytes in scaffolds grafted with TATVHL peptide,"
Colloids Surf. B 93, 235–240. 
61. Kuo, Y. C.* and C. Y. Chung, 2012, 05, "Chondrogenesis in scaffolds
with surface modification of elastin and poly-L-lysine," Colloids Surf. B
93, 85–91. 
62. Lyu, S. R., Y. C. Kuo*, M. H. Lin, W. H. Hsieh, and C. W. Chuang, 2012,
03, "Application of albumin-grafted scaffolds to promote neocartilage
formation," Colloids Surf. B 91, 296–301. 

63. Kuo, Y. C.* and C. H. Lu, 2012, 03, "Modulation of efflux proteins by
electromagnetic field for delivering azidothymidine and saquinavir into
the brain," Colloids Surf. B 91, 291–295. 
64. Kuo, Y. C.* and C. Y. Chung, 2012, 03, "Transcytosis of CRM197-grafted
polybutylcyanoacrylate nanoparticles for delivering zidovudine across
human brain-microvascular endothelial cells," Colloids Surf. B 91,
242–249. 
65. Kuo, Y. C.* and C. H. Lu, 2012, 03, "Expression of P-glycoprotein and
multidrug resistance-associated protein on human brain-microvascular
endothelial cells with electromagnetic stimulation," Colloids Surf. B 91,
57–62. 
66. Kuo, Y. C.* and C. L. Lee, 2012, 02,
"Methylmethacrylate–sulfopropylmethacrylate nanoparticles with surface
RMP-7 for targeting delivery of antiretroviral drugs across the
blood–brain barrier," Colloids Surf. B 90, 75–82. 
67. Kuo, Y. C.* and C. Y. Chung, 2011, 12, "Solid lipid nanoparticles
comprising internal Compritol 888 ATO, tripalmitin and cacao butter for
encapsulating and releasing stavudine, delavirdine and saquinavir,"
Colloids Surf. B 88, 682–690. 
68. Kuo, Y. C.* and H. W. Yu, 2011, 12, "Expression of ornithine
decarboxylase during the transport of saquinavir across the blood–brain
barrier using composite polymeric nanocarriers under an electromagnetic
field," Colloids Surf. B 88, 627–634. 
69. Lin, S. H.*, J. P. Hsu, S. Tseng, Y. C. Kuo, and B. T. Liu, 2011, 11, "EDL
configuration on a dissimilarly-charged protrusion array via double
Fourier series and perturbation method," Colloids Surf. B 88, 527–533. 
70. Kuo, Y. C.* and H. W. Yu, 2011, 11, "Polyethyleneimine/poly-(γ-glutamic
acid)/poly(lactide-co-glycolide) nanoparticles for loading and releasing
antiretroviral drug," Colloids Surf. B 88, 158–164. 

71. Kuo, Y. C.* and C. H. Lu, 2011, 10, "Regulation of endocytosis into
human brain-microvascular endothelial cells by inhibition of efflux
proteins," Colloids Surf. B 87, 139–145. 
72. Kuo, Y. C.* and H. W. Yu, 2011, 09, "Transport of saquinavir across
human brain-microvascular endothelial cells by poly(lactide-co-glycolide)
nanoparticles with surface poly-(γ-glutamic acid)," Int. J. Pharm. 416,
365–375. 
73. Lin, S. H.*, J. P. Hsu, S. Tseng, Y. C. Kuo, and B. T. Liu, 2011, 09,
"Solving EDL configuration near a dissimilarly-charged protrusions
surface model using perturbation method," Colloids Surf. B 86, 370–377. 
74. Kuo, Y. C.* and C. H. Lu, 2011, 08, "Effect of human astrocytes on the
characteristics of human brain-microvascular endothelial cells in the
blood–brain barrier," Colloids Surf. B 86, 225–231. 
75. Kuo, Y. C.*, P. I. Lin, and C. C. Wang, 2011, 08, "Targeting nevirapine
delivery across human brain microvascular endothelial cells using
transferrin-grafted poly(lactide-co-glycolide) nanoparticles,"
Nanomedicine 6, 1011–1026. 
76. Kuo, Y. C.* and C. T. Liang, 2011, 07, "Catanionic solid lipid
nanoparticles carrying doxorubicin for inhibiting the growth of U87MG
cells," Colloids Surf. B 85, 131–137. 
77. Kuo, Y. C.* and H. W. Yu, 2011, 05, "Surface coverage of didecyl
dimethylammonium bromide on poly(lactide-co-glycolide) nanoparticles,"
Colloids Surf. B 84, 253–258.  
78. Yang, J. T., Y. C. Kuo*, and K. H. Chiu, 2011, 05, "Peptide-modified
inverted colloidal crystal scaffolds with bone marrow stromal cells in the
treatment for spinal cord injury," Colloids Surf. B 84, 198–205. 
79. Kuo, Y. C.* and C. C. Wang, 2011, 05, "Surface modification with peptide
for enhancing chondrocyte adhesion and cartilage regeneration in porous
scaffolds," Colloids Surf. B 84, 63–70. 
80. Kuo, Y. C.* and C. T. Liang, 2011, 04, "Inhibition of human brain
malignant glioblastoma cells using carmustine-loaded catanionic solid

lipid nanoparticles with surface anti-epithelial growth factor receptor,"
Biomaterials 32, 3340–3350.  (Selected in Global Medical Discovery
Series) 
81. Kuo, Y. C.* and J. F. Chung, 2011, 04, "Physicochemical properties of
nevirapine-loaded solid lipid nanoparticles and nanostructured lipid
carriers," Colloids Surf. B 83, 299–306. 
82. Kuo, Y. C.* and C. F. Yeh, 2011, 02, "Effect of surface-modified collagen
on the adhesion, biocompatibility and differentiation of bone marrow
stromal cells in poly(lactide-co-glycolide)/chitosan scaffolds," Colloids
Surf. B 82, 624–631. 
83. Kuo, Y. C.* and Y. T. Tsai, 2011, 02, "Heparin-conjugated scaffolds with
pore structure of inverted colloidal crystals for cartilage regeneration,"
Colloids Surf. B 82, 616–623. 
84. Kuo, Y. C.* and K. H. Chiu, 2011, 01, "Inverted colloidal crystal scaffolds
with laminin-derived peptides for neuronal differentiation of bone marrow
stromal cells," Biomaterials 32, 819–831. 
85. Kuo, Y. C.* and H. H. Chen, 2010, 07, "Effect of electromagnetic field on
endocytosis of cationic solid lipid nanoparticles by human brain-
microvascular endothelial cells," J. Drug Target. 18, 447–456.  
86. Kuo, Y. C.* and Y. T. Tsai, 2010, 03, "Inverted colloidal crystal scaffolds
for uniform cartilage regeneration," Biomacromolecules 11, 731–739. 
87. Kuo, Y. C.* and C. C. Wang, 2010, 03, "Effect of bovine pituitary extract
on the formation of neocartilage in chitosan/gelatin scaffolds," J. Taiwan
Inst. Chem. Eng. 41, 150–156. 
88. Wu, H. C.*, Y. C. Kuo, Y. H. Wang, C. W. Wu, and H. C. Hsiao, 2010, 03,
"Study on safe air transporting velocity of nanograde aluminum, iron, and
titanium," J. Loss Prev. Process Ind. 23, 308–311. 
89. Kuo, Y. C.* and C. C. Wang, 2010, 03, "Electrophoresis of human brain
microvascular endothelial cells with uptake of cationic solid lipid
nanoparticles: effect of surfactant composition," Colloids Surf. B 76,
286–291. 

90. Kuo, Y. C.* and S. N. Leou, 2010, 02, "Chondrogenesis of articular
chondrocytes in hydroxyapatite/chitin/chitosan scaffolds supplemented
with pituitary extract," Eng. Life Sci. 10, 67–74. 
91. Kuo, Y. C.*, K. H. Shih, and J. T. Yang, 2010, 01, "Capillary
electrophoresis of bone marrow stromal cells with the uptake of heparin-
functionalized poly(lactide-co-glycolide) nanoparticles during
differentiation towards neurons," Electrophoresis 31, 315–323. 
92. Kuo, Y. C.*, C. F. Yeh, and J. T. Yang, 2009, 12, "Differentiation of bone
marrow stromal cells in poly(lactide-co-glycolide)/chitosan scaffolds,"
Biomaterials 30, 6604–6613.  (Printed in the year in images)
93. Kuo, Y. C.* and Y. R. Hsu, 2009, 10, "Tissue-engineered polyethylene
oxide/chitosan scaffolds as potential substitutes for articular cartilage," J.
Biomed. Mater. Res. A 91, 277–287. 
94. Kuo, Y. C.* and C. W. Lin, 2009, 09, "Impact of arginine-modified solid
lipid nanoparticles on the membrane charge of human brain-
microvascular endothelial cells," Colloids Surf. B 72, 201–207. 
95. Kuo, Y. C.* and I. N. Ku, 2009, 09, "Application of polyethyleneimine-
modified scaffolds to the regeneration of cartilaginous tissue," Biotechnol.
Prog. 25, 1459–1467. 
96. Kuo, Y. C.* and K. H. Shih, 2009, 07, "Loading efficiency and surface
conductance of heparin-modified poly(lactide-co-glycolide)
nanoparticles," Colloids Surf. B 71, 282–287. 
NSC96–2221–E–194–036–MY3 
97. Kuo, Y. C.* and C. W. Lin, 2009, 06, "Effect of electromagnetic field and
surface modification on the electrical behavior of novel solid lipid
nanoparticles covered with L-arginine," Colloids Surf. B 71, 45–51. 
NSC96–2221–E–194–036–MY3 
98. Kuo, Y. C.* and H. H. Chen, 2009, 01, "Entrapment and release of
saquinavir using novel cationic solid lipid nanoparticles," Int. J. Pharm.
365, 206–213. 

99. Kuo, Y. C.* and I. N. Ku, 2008, 10, "Cartilage regeneration by novel
polyethylene oxide/chitin/chitosan scaffolds," Biomacromolecules 9,
2662–2669. 
100. Kuo, Y. C.* and S. C. Lin, 2008, 04, "Effect of glutamate on the
electrical properties of cationic solid lipid nanoparticles containing
stearylamine and dioctadecyldimethyl ammonium bromide," J. Phys.
Chem. B 112, 4454–4460.  NSC96–2221–E–194–036–MY3 
101. Kuo, Y. C.*, H. K. Huang, and H. C. Wu, 2008, 04, "Thermal
characteristics of aluminum nanoparticles and oilcloths," J. Hazard.
Mater. 152, 1002–1010.  IOSH94–S101 
102. Kuo, Y. C.* and C. Y. Kuo, 2008, 03, "Electromagnetic interference in
the permeability of saquinavir across the blood–brain barrier using
nanoparticulate carriers," Int. J. Pharm. 351, 271–281. 
103. Kuo, Y. C.* and I. C. Chen, 2007, 09, "Evaluation of surface charge
density and surface potential by electrophoretic mobility for solid lipid
nanoparticles and human brain-microvascular endothelial cells," J. Phys.
Chem. B 111, 11228–11236. 
104. Kuo, Y. C.* and F. L. Su, 2007, 08, "Transport of stavudine, delavirdine,
and saquinavir across the blood–brain barrier by polybutylcyanoacrylate,
methylmethacrylate–sulfopropylmethacrylate, and solid lipid
nanoparticles," Int. J. Pharm. 340, 143–152. 
105. Kuo, Y. C.* and I. N. Ku, 2007, 02, "Effects of gel concentration, human
fibronectin, and cation supplement on the tissue-engineered cartilage,"
Biotechnol. Prog. 23, 238–245. 
106. Kuo, Y. C.* and S. N. Leou, 2006, 12, "Effects of composition, solvent,
and salt particles on the physicochemical properties of
polyglycolide/poly(lactide-co-glycolide) scaffolds," Biotechnol. Prog. 22,
1664–1670. 
107. Kuo, Y. C.* and H. H. Chen, 2006, 12, "Effect of nanoparticulate
polybutylcyanoacrylate and methylmethacrylate–sulfopropylmethacrylate

on the permeability of zidovudine and lamivudine across the in vitro
blood–brain barrier," Int. J. Pharm. 327, 160–169. 
108. Kuo, Y. C.* and C. Y. Lin, 2006, 09, "Effect of genipin-crosslinked
chitin–chitosan scaffolds with hydroxyapatite modifications on the
cultivation of bovine knee chondrocytes," Biotechnol. Bioeng. 95,
132–144. 
109. Kuo, Y. C.* and T. W. Lin, 2006, 02, "Electrophoretic mobility, zeta
potential, and fixed charge density of bovine knee chondrocytes, methyl
methacrylate-sulfopropyl methacrylate, polybutylcyanoacrylate, and solid
lipid nanoparticles," J. Phys. Chem. B 110, 2202–2208. 
110. Kuo, Y. C.*, 2005, 12, "Critical coagulation concentration for a
suspension of cation-absorptive biocolloids," Colloids Surf. B 46,
218–225.  NSC 94–2214–E–194–001– 
111. Kuo, Y. C.* and C. Y. Chung, 2005, 12, "Application of bovine pituitary
extract and polyglycolide/poly(lactide-co-glycolide) scaffold to the
cultivation of bovine knee chondrocytes," Biotechnol. Prog. 21,
1708–1715. 
112. Kuo, Y. C.* and C. Y. Chung, 2005, 11, "Transport of zidovudine- and
lamivudine-loaded polybutylcyanoacrylate and methylmethacrylate-
sulfopropylmethacrylate nanoparticles across the in vitro blood–brain
barrier: characteristics of the drug-delivery system," J. Taiwan Inst.
Chem. Eng. 36, 627–638. 
113. Kuo, Y. C.*, 2005, 08, "Deposition of cation-absorptive biocolloids onto
a charged surface," J. Colloid Interface Sci. 288, 36–44.  NSC
92–2214–E–194–008– 
114. Kuo, Y. C.*, 2005, 06, "Electrophoresis of a biocolloid covered with a
cation-absorptive membrane," J. Phys. Chem. B 109, 11727–11734. 
NSC 93–2214–E–194–005– 
115. Kuo, Y. C.*, 2005, 02, "Loading efficiency of stavudine on
polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate
copolymer nanoparticles," Int. J. Pharm. 290, 161–172. 

116. Kuo, Y. C.*, 2004, 03, "Effect of non-instantaneous disposition on the
general measures of distribution kinetics in a modified mammillary
compartmental model," J. Chin. Inst. Eng. 27, 231–242. 
117. Kuo, Y. C.*, 2003, 07, "Application of a modified Gouy-Chapman theory
to the stability of a biocolloidal suspension," Langmuir 19, 5942–5948. 
118. Hsu, J. P.*, S. W. Huang, Y. C. Kuo, and S. J. Tseng, 2003, 06,
"Stability of a dispersion of particles covered by a charge-regulated
membrane: effect of the sizes of charged species," J. Colloid Interface
Sci. 262, 73–80. 
119. Kuo, Y. C.*, 2003, 03, "Adsorption of a biocolloid onto a rigid charged
surface: characteristics of functional group, membrane and electrolytic
solution," J. Taiwan Inst. Chem. Eng. 34, 117–186. 
120. Kuo, Y. C.*, 2003, 05, "Effects of particulate curvature and sizes of
charged species on the adsorption of a biocolloid bearing nonuniformly
distributed fixed charges," J. Chem. Phys. 118, 8023–8032. 
121. Kuo, Y. C.*, 2003, 01, "Effects of sizes of charged species on the
flocculation of biocolloids: absorption of cations in the membrane layer,"
J. Chem. Phys. 118, 398–406. 
122. Hsu, J. P.*, S. W. Huang, Y. C. Kuo, and S. J. Tseng, 2002, 04, "Effect
of ionic sizes on critical coagulation concentration: particle covered by a
charge-regulated membrane," J. Phys. Chem. B 106, 4269–4275. 
123. Kuo, Y. C.*, M. Y. Hsieh, and J. P. Hsu, 2002, 04, "Deposition of
charge-regulated biocolloids on a charged surface," J. Phys. Chem. B
106, 4255–4260. 
124. Kuo, Y. C., M. Y. Hsieh, and J. P. Hsu*, 2002, 04, "Interactions between
a particle covered by an ion-penetrable charged membrane and a
charged surface: a modified Gouy-Chapman theory," Langmuir 18,
2789–2794. 
125. Huang, S. W., J. P. Hsu*, Y. C. Kuo, and S. J. Tseng, 2002, 02, "Effect
of ionic sizes on the electrophoretic mobility of a particle with a charge-

regulated membrane in a general electrolyte solution," J. Phys. Chem. B
106, 2117–2122. 
126. Hsu, J. P.*, C. H. Lu, Y. C. Kuo, and S. J. Tseng, 2001, 08, "Electrical
interaction between two cylinders with an ion-penetrable charged
membrane in an oil/water interface," Colloids Surf. B 21, 265–272. 
127. Kuo, Y. C.*, J. P. Hsu, and D. F. Chen, 2001, 05, "Deposition of
biocolloids on a charged collector surface: an ion-penetrable membrane
model," Langmuir 17, 3466–3471. 
128. Kuo, Y. C. and J. P. Hsu*, 2000, 07, "Electrical interactions between two
ion-penetrable charged membranes: effect of sizes of charged species,"
Langmuir 16, 6233–6239. 
129. Kuo, Y. C. and Y. W. Chen*, 2000, 09, "Thermal properties of
chrominophosphates," J. Taiwan Inst. Chem. Eng. 31, 487–492. 
130. Kuo, Y. C. and Y. W. Chen*, 2000, 01, "Isopropyl alcohol dehydration
over chrominophosphate catalysts II: deactivation," J. Taiwan Inst.
Chem. Eng. 31, 1–9. 
131. Kuo, Y. C. and J. P. Hsu*, 1999, 12, "Dynamic stability ratio of a
colloidal dispersion," Chem. Phys. 250, 285–294. 
132. Kuo, Y. C. and J. P. Hsu*, 1999, 11, "Double-layer properties of an ion-
penetrable charged membrane: effect of sizes of charged species," J.
Phys. Chem. B 103, 9743–9748. 
133. Kuo, Y. C. and Y. W. Chen*, 1999, 09, "Isopropyl alcohol dehydration
over chrominophosphate catalysts I: a kinetic study," J. Taiwan Inst.
Chem. Eng. 30, 421–429. 
134. Hsu, J. P.* and Y. C. Kuo, 1999, 09, "Modified Göuy-Chapman theory
for ion-penetrable charged membranes," J. Chem. Phys. 111,
4807–4816. 
135. Kuo, Y. C. and J. P. Hsu*, 1999, 09, "Electrical properties of charged
cylindrical and spherical surfaces in a general electrolyte solution,"
Langmuir 15, 6244–6255. 

136. Kuo, Y. C. and J. P. Hsu*, 1998, 09, "Electrical properties of a charged
surface in a general electrolyte solution," Chem. Phys. 236, 1–14. 
137. Kuo, Y. C. and J. P. Hsu*, 1998, 03, "Transient behaviors of interacting
electrical double layers," Colloid Polym. Sci. 276, 213–218. 
138. Hsu, J. P.*, Y. C. Kuo, and S. J. Tseng, 1997, 11, "Dynamic interactions
of two electrical double layers," J. Colloid Interface Sci. 195, 388–394. 
139. Hsu, J. P.* and Y. C. Kuo, 1997, 08, "Adsorption of a charge-regulated
particle to a charged surface," Langmuir 13, 4372–4376. 
140. Hsu, J. P.* and Y. C. Kuo, 1997, 01, "The critical coagulation
concentration of counterions: spherical particles in asymmetric electrolyte
solutions," J. Colloid Interface Sci. 185, 530–537. 
141. Hsu, J. P.* and Y. C. Kuo, 1996, 10, "The electrostatic interaction force
between a charge-regulated particle and a rigid surface," J. Colloid
Interface Sci. 183, 194–198. 
142. Hsu, J. P.* and Y. C. Kuo, 1996, 10, "The stability ratio for a dispersion
of particles covered by an ion-penetrable charged membrane," J. Colloid
Interface Sci. 183, 184–193. 
143. Hsu, J. P.* and Y. C. Kuo, 1995, 12, "Properties of a double layer with
asymmetric electrolytes: ion-penetrable membrane carrying nonuniformly
distributed fixed charges," J. Membr. Sci. 108, 107–119. 
144. Hsu, J. P.* and Y. C. Kuo, 1995, 12, "Net penetration charges of an ion-
penetrable membrane in a general electrolyte solution," J. Colloid
Interface Sci. 176, 256–263. 
145. Hsu, J. P.* and Y. C. Kuo, 1995, 11, "Interactions between a charge-
regulated particle and a charged surface," J. Chem. Soc. Faraday Trans.
91, 4093–4097. 
146. Hsu, J. P.* and Y. C. Kuo, 1995, 09, "An algorithm for the calculation of
the electrostatic repulsion between surfaces coated with a charged
membrane," Colloid Polym. Sci. 273, 881–885. 

147. Hsu, J. P.* and Y. C. Kuo, 1995, 09, "Critical coagulation concentration
of cations for negatively charged particles with an ion-penetrable surface
layer," J. Colloid Interface Sci. 174, 250–257. 
148. Hsu, J. P.* and Y. C. Kuo, 1995, 07, "Electrostatic interactions between
particles with an ion-penetrable charged membrane," J. Chem. Phys.
103, 465–473. 
149. Hsu, J. P.* and Y. C. Kuo, 1995, 05, "An algorithm for the calculation of
the electrostatic potential distribution of an ion-penetrable membrane
carrying fixed charges," J. Colloid Interface Sci. 171, 483–489. 
150. Hsu, J. P.* and Y. C. Kuo, 1995, 05, "Properties of a double layer with
asymmetric electrolytes: cylindrical and spherical particles with an ion-
penetrable membrane," J. Colloid Interface Sci. 171, 331–339. 
151. Hsu, J. P.* and Y. C. Kuo, 1995, 04, "Solution to the Poisson-Boltzmann
equation for particles covered by an ion-penetrable charged membrane,"
J. Chem. Soc. Faraday Trans. 91, 1223–1228. 
152. Hsu, J. P.* and Y. C. Kuo, 1995, 04, "An extension of the Schulze-
Hardy rule to asymmetric electrolytes," J. Colloid Interface Sci. 171,
254–255. 
153. Hsu, J. P.* and Y. C. Kuo, 1995, 03, "Approximate analytical expression
for surface potential as a function of surface charge density," J. Colloid
Interface Sci. 170, 220–228. 
154. Kuo, Y. C. and J. P. Hsu*, 1995, 01, "Exact solution of the linearized
Poisson-Boltzmann equation: ion-penetrable membrane bearing fixed
charges," J. Chem. Phys. 102, 1806–1815. 
155. Hsu, J. P.* and Y. C. Kuo, 1994, 10, "Approximate analytical
expressions for the properties of an electrical double layer with
asymmetric electrolytes: cylindrical and spherical geometries," J. Colloid
Interface Sci. 167, 35–46. 
156. Hsu, J. P.*, Y. C. Kuo, and Y. I. Chang, 1994, 08, "Electrostatic
interaction between a charge-regulated particle and a solid surface in

electrolyte solution: effect of cationic electrolytes," Colloid Polym. Sci.
272, 946–954. 
157. Hsu, J. P.* and Y. C. Kuo, 1994, 08, "Approximate analytical
expressions for the properties of a double layer with asymmetric
electrolytes: ion-penetrable charged membrane," J. Colloid Interface Sci.
166, 208–214. 
158. Hsu, J. P.* and Y. C. Kuo, 1993, 04, "Approximate analytical
expressions for the properties of an electrical double layer with
asymmetric electrolytes," J. Chem. Soc. Faraday Trans. 89, 1229–1233. 
159. Kuo, Y. C. and J. P. Hsu*, 1993, 03, "An algorithm for the calculation of
the electrostatic force between identical charged surfaces in
electrolytes," J. Colloid Interface Sci. 156, 250–252. 
160. Chen, Y. W.* and Y. C. Kuo, 1992, 03, "The pore structure of
chrominophosphate catalysts," Catal. Lett. 13, 137–142.