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Postdoctoral Researcher

Dr. Sourav De

ACADEMIC EXPERIENCE

Ph.D (Chemistry) : VIT, Vellore, Tamil Nadu, India.

Title of Dissertation: Design, Synthesis, Characterization and Anticancer Evaluation of Various Heterocycles and Ru(II)-Arene-N^N, N^O, N^S Complexes

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M. Pharm (Pharmaceutical Chemistry): West Bengal University of Technology, West Bengal, India, First class. (87.9%)

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B. Pharm (Chemistry): North Bengal University, Sikkim, West Bengal, India, ​First class. (74%)

WORK EXPERIENCE

August 2022-till date

Postdoctoral Researcher, Department of Chemical Engineering, College of Engineering, National Chung Cheng University, Chia-Yi, Taiwan 62102.

January 2021-July 2022

Assistant Professor at Department of Pharmaceutical Technology, School of Medical Sciences, Adamas University, Kolkata-700126, India

January 2018-December 2020

Project Assistant, Department of Science and Technology, Government of India-SERB (EMR)

​April 2017- December 2017

Research Associate at School of Advanced Sciences, VIT, Vellore - 632014.

Assisting B.Tech., students to carry out the experimental works in engineering chemistry lab

July 2012-March 2017

Assistant Professor at Department of Pharmaceutical Technology, Jawaharlal Nehru Technological University, Anantapur, Andhra Pradesh, India

EXPERIENCED RESEARCH FIELD

  1. Organic and Bio-inorganic based drug delivery system for Diabetes disease, Parkinson’s disease and cancer treatment.
  2. Therapeutic applications of organic and organo-metallic Complexes
  3. Designing of new molecules via molecular docking
  4. Chromogenic and Fluorogenic sensors

PROFICIENT KNOWLEDGE IN INTERPRETING ANALYSIS

  1. UV-VIS-NIR Spectroscopy
  2. Fluorescence Spectroscopy
  3. NMR Spectroscopy
  4. TG/DTA
  5. FT-IR Spectroscopy
  6. Powder XRD
  7. FE-SEM and EDAX
  8. Flowcytometry
  9. Elisa Reader
  10. Gel Documentation
  11. Universal Testing Machine

JOURNAL PUBLICATIONS

  1. P. Selvam†, Sourav De†, R. Selva Kumar, A. Moorthy, A. Ghosh, Y.-C Kuo, S. Banerjee, P. Paira, S. K. Ashok Kumar, In vitro Studies on the Selective Cytotoxic Effect of Luminescent Ru(II)-p-Cymene Complexes of Imidazo-Pyridine and Imidazo Quinoline Ligands, Dalton Trans., Revision Submitted. Impact factor- 4.569
  2. Sourav De, Ashok Kumar S K, Suraj Kumar Shah, Sabnaz Kazi, Nandan Sarkar, Subhasis Banerjee and Sanjay Dey, Pyridine: the scaffolds with significant clinical diversity, RSC Adv., 2022,12, 15385-15406. Impact factor: 4.036
  3. Sourav De, R. Selva Kumar, G. Ashna, S K Ashok Kumar, P. Paira, A. Moorthy, S. Banerjee, Luminescent Ruthenium(II)-para-cymene complexes of aryl substituted imidazo-1,10-phenanthroline as anticancer agents and the effect of remote substituents on cytotoxic activities, Inorg. Chim. Acta 515 (2021) 120066. Impact factor: 3.118
  4. B. Kar, U. Das, Sourav De, S. Pete, A. Sharma S, N. Roy, Ashok Kumar S K, D. Panda, P. Paira, GSH resistant and highly cytoselective Ru(II)-p-cymene-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenol complexes as potential anticancer agent, Dalton Trans., 50 (2021) 10369-10373. Impact factor: 4.569
  5. B. Kar, S. Shanavas, A. H. Nagendra, U. Das, N. Roy, S. Pete, A. Sharma, Sourav De, Ashok Kumar SK, S. Vardhan, S. K Sahoo, D. Panda, S. Shenoy, B. Bose, P. Paira, Iridium(iii)–Cp*-(imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenol analogues as hypoxia active, GSH-resistant cancer cytoselective and mitochondria-targeting cancer stem

cell therapeutic agents, Dalton Trans., 2022,51, 5494-5514. Impact

factor-4.569

  1. Sourav De, S K Ashok Kumar, Highly selective and potent anti-cancer agents based on 2,9-substituted-1,10-phenanthroline derivatives, Inorg. Chem. Commun. 119 (2020) 108085. Impact factor: 3.428
  2. Sourav De, S K Ashok Kumar, Development of highly potent Arene-Ru (II)-ninhydrin complexes for inhibition of cancer cell growth, Inorg. Chim. Acta 508 (2020) 119641. Impact factor: 3.118
  3. S. Maiti, N. Roy, L. T. Babu, P. Moharana, Athira C C, D. Sreedhar E, Sourav De, Ashok Kumar S K and P. Paira, Cu(II), Ir(I) and CuO nanocatalyzed mild synthesis of luminescent symmetrical and unsymmetrical bis(triazolylmethyl)quinoxalines: biocompatibility, cytotoxicity, live cell imaging and biomolecular interaction, New J. Chem. 44 (2020) 920-931. Impact factor: 3.925
  4. Sourav De, S. R. Chaudhuri, A. Panda, G. R. Jadhav, R. Selva Kumar, M. Prasanth, N. Ramesh, A. Mondal, M. Anbalagan, S. Banerjee, P. Paira, S. K. Ashok Kumar, Synthesis, characterization, molecular docking, biomolecular interaction and cytotoxicity studies of novel Ru(II)-arene- 2-heteroarylbenzoxazole complexes, New J. Chem. 43 (2019) 3291-3302. Impact factor: 3.925
  5. Sourav De, S. Banerjee, Ashok Kumar S K, P. Paira, Critical role of Dipeptidyl Peptidase IV: A therapeutic target for cancer & diabetes. Mini-Rev. Med. Chem. 19 (2019) 88-97. Impact factor: 3.737
  6. Sourav De, Sunisha K S, R. Selva kumar, S. Banerjee, Ashok Kumar S K and P. Paira, Luminescent Anticancer Acenaphtho[1,2-b]quinoxaline: Green Synthesis, DFT and Molecular Docking Studies, Live-Cell Imaging and Reactivity towards Nucleic Acid and Protein BSA, Chemistry Select 3 (2018) 5421–5430. Impact factor: 2.307
  7. Sourav De, B. Sarkar, G. R. Jadhav, R. Selva kumar, S. Banerjee, M. Anbalagan, P. Paira and S K Ashok Kumar, Experimental and Theoretical Study on the Biomolecular Interaction of Novel Acenaphtho quinoxaline and Dipyridophenazine analogues, Chemistry Select 3 (2018) 10593-10602. Impact factor: 2.307
  8. M. Vijaya Bharathi†, Sourav De†, T. Lavanya, S. Maiti, B. Sarkar, S. K. Ashok Kumar and P. Paira, Surface immobilization of biotin-DNA conjugates on polystyrene beads via SPAAC for biological interaction and cancer theranostic applications, New J. Chem. 42 (2018) 9116-9125. [†Equal Contribution]. Impact factor: 3.925
  9. A Mondal, Sourav De, S. Maiti, B. Sarkar, Ashok Kumar S K, Rini Jacob, M. Anbalagan, P. Paira. Amberlite IR-120 (H) mediated “on water” synthesis of fluorescent Ruthenium (II)-arene 8-hydroxyquinoline complexes for cancer therapy and live cell imaging, J. Photochem. Photobiol., B      178 (2018) 380-394. Impact factor: 6.814
  10. Sourav De, S. Banerjee, M. Niranjan Babu, B. Mohana Lakshmi, T. M. Suneel Babu. Review on Cardiac Glycosides in Cancer Research and Cancer Therapy, Indo American Journal of Pharmaceutical Research. 6 (2016) 5391-5400. I.F – 4.587
  11. Sourav De, S. Banerjee, Structure Based Design of Few Substituted Piperidones as Dipeptidyl Peptidase Inhibitors, International Journal of Pharmacy and Pharmaceutical Sciences, 4 (2012) 163-170. I.F- 2.029

Book Chapter

  • Study of Few Polysubstituted Piperidone Analogs. Sourav De, Subhasis Banerjee, Publisher: LAP Lambert Academic Publishing AG & Co KG. ISBN-9783848404971 Published 27/12/2012
  • Study of Few Tetralone Analogs. Sourav De, Subhasis Banerjee; Publisher: LAP Lambert Academic Publishing AG & Co KG.  ISBN- 978-3-659-87740-7 Published 04/05/2016

Patent

  • Sourav De, Sanjay Dey, Sajal Kumar Jha, Anwesha Barik, Suraj Kumar Shah, A system for the production of zingiberol-loaded microspheres using a mixture of sodium alginate and methylcellulose, Patent number-20 2021 106 657.1, Patent office DE, 2022

CONFERENCE PRESENTATIONS                          

  • Presented a poster entitled “Synthesis, characterization and nucleic acid interactions of phenanthroline derivatives for cytotoxicity studies” in ‘26th National Symposium in Chemistry (CRSI-NSC-26)’ held at VIT, Vellore. (7th to 9th Feb 2020).
  • Presented a poster entitled “Luminescent Ru(II)-arene-phenanthroline Complexes for theranostic Applications” in ‘International Conference on Chemical Sciences and Nanomaterials (ICCSN-2019)’ held at VIT, Vellore (7th to 9th March 2019).
  • Presented a poster entitled “Synthesis and characterisation of Ru(II)-ninhydrin based Schiff’s bases for nucleic acid interactions” in ‘VIT-RSC symposium on Advances in Chemical Sciences’ held at VIT, Vellore (5th Feb 2019).
  • Presented a poster entitled “Development of Ru(II)–arene-2- heteroarylbenzoxazole complexes for antimicrobial studies” in ‘International conference on Bacteriophage Research and Antimicrobial Resistance (ICBRAMR-19) held at VIT, Vellore (12th to 13th Dec 2019).
  • Presented a poster entitles “Amberlite IR-120 (H) Mediated “On Water” Synthesis of Anticancer Ruthenium(II)-Arene-8-Hydroxyquinoline Complexes” in 5th Symposium on Advanced Biological Inorganic Chemistry (SABIC 2017)’ held in Stadel, Kolkata, (7th to 11th Oct 2016).
  • Presented an oral entitles “Structure based design of few substituted piperidones as dipeptidyl peptidase inhibitors” in AICTE sponsored held at Gupta College of Technological Sciences, Asansol (7th to 8th 2012).
  • Presented a poster entitles “In-silico design of few substituted pyridine as dipeptidyl peptidase inhibitors” in Science Engineering Research Board (SERB) sponsored one day national conference held at Koringa College of Pharmacy (26th March, 2016)

AWARDS AND ACCOMPLISHMENTS

  1. Teaching Excellence Award- 2021, ADAMAS University, India
  2. RSC New Journal of Chemistry best poster award for abstract entitled “Synthesis, Characterization and In-Vitro Cytotoxic Evaluation of Ru(II) based Imidazo-1,10-Phenanthroline Derivatives” in Virtual International Conference on “Molecules to Materials” held at S.V. National Institute of Technology, Surat, India, (17th -18th Dec 2020)
  3. Research award from VIT University for the research publications (for the consecutive three years 2019, 2020)

As a Reviewer

  1. RSC Advanced

 Advanced in Science, Technology and Engineering Systems Journal (ASTESJ)

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